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>   首页   >   产品   >   一抗   >   其他   >   Polyclonal Antibody to Angiopoietin Like Protein 4 (ANGPTL4)   

Polyclonal Antibody to Angiopoietin Like Protein 4 (ANGPTL4)

Angiopoietin Like Protein 4

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q2KJ51
Host Rabbit
Clonality Polyclonal
Calculated MW 45553 Da
Additional Information
Gene ID 509963
Other Names ARP4; FIAF; HFARP; NL2; PGAR; Pp1158; Fasting-Induced Adipose Factor; Hepatic Angiopoietin-Related Protein; Hepatic Fibrinogen/Angiopoietin-Related Protein
Target/Specificity Bos taurus; Bovine (Cattle)
Dilution WB~~Western blotting: 0.2-2 µg/mL;1:250-2500
Immunohistochemistry: 5-20 µg/mL;1:25-100
Immunocytochemistry: 5-20 µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Format PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name ANGPTL4
Function Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (By similarity).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q9Z1P8}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q9BY76}. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4 {ECO:0000250|UniProtKB:Q9BY76}
Research Areas
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