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>   首页   >   产品   >   一抗   >   其他   >   Polyclonal Antibody to Natural Cytotoxicity Triggering Receptor 3 (NCR3)   

Polyclonal Antibody to Natural Cytotoxicity Triggering Receptor 3 (NCR3)

Natural Cytotoxicity Triggering Receptor 3

     
  • 1 - Polyclonal Antibody to Natural Cytotoxicity Triggering Receptor 3 (NCR3) AP74764
    Figure. Western Blot; Sample: Recombinant NCR3, Rat.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q8CFD9
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 20470 Da
Additional Information
Other Names CD337; 1C7; LY117; NKp30; Lymphocyte Antigen 117; Activating natural killer receptor p30; Natural killer cell p30-related protein
Target/Specificity Rattus norvegicus (Rat)
Dilution WB~~Western blotting: 0.5-2 µg/mL;<br/>Immunohistochemistry: 5-20 µg/mL;<br/>Immunocytochemistry: 5-20 µg/mL;<br/>Optimal working dilutions must be determined by end user.
Format PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
StorageStore at -20 °C.Stable for 12 months from date of receipt

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name Ncr3
Synonyms 1c7
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:O14931}; Single-pass type I membrane protein
Research Areas
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