癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Polyclonal Antibody to Complement Component 5a (C5a)
Complement Component 5a
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | P01032 |
| Reactivity | Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 8609 Da |
| Other Names | Complement C5a anaphylatoxin, C5 |
|---|---|
| Target/Specificity | Sus scrofa; Porcine (Pig) |
| Dilution | WB~~Western blotting: 0.5-2 µg/mL<br/>Immunohistochemistry: 5-20 µg/mL<br/>Immunocytochemistry: 5-20 µg/mL<br/>Optimal working dilutions must be determined by end user. |
| Format | PBS, pH7.4, containing 0.02% NaN3, 50% glycerol. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | C5 |
|---|---|
| Function | Mediator of local inflammatory process released following cleavage by C5 convertase. Acts by binding to its receptor (C5AR1 or C5AR2), activating G protein-coupled receptor signaling and inducing a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. |
| Cellular Location | Secreted. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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