CD32B Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IHC-P |
---|---|
Primary Accession | P31994 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 34044 Da |
Gene ID | 2213 |
---|---|
Other Names | FCGR2B |
Dilution | WB~~1/500-1/1000 IHC-P~~N/A |
Format | Liquid |
Name | FCGR2B |
---|---|
Synonyms | CD32, FCG2, IGFR2 |
Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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