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>   首页   >   产品   >   一抗   >   其他   >   CD32B Rabbit mAb   

CD32B Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession P31994
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 34044 Da
Additional Information
Gene ID 2213
Other Names FCGR2B
Dilution WB~~1/500-1/1000
IHC-P~~N/A
Format Liquid
Protein Information
Name FCGR2B
Synonyms CD32, FCG2, IGFR2
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Is the most broadly distributed Fc-gamma-receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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