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StAR Rabbit mAb

     
  • 1 - StAR Rabbit mAb AP74919
    Western blot analysis of StAR in K562, 3T3, Hela lysates using StAR antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P
Primary Accession P49675
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 31914 Da
Additional Information
Gene ID 6770
Other Names STAR
Dilution WB~~1:2000-1:5000
IHC-P~~1:50~200
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name STAR (HGNC:11359)
Synonyms STARD1
Function Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
Cellular Location Mitochondrion outer membrane. Mitochondrion matrix. Note=Works only on the mitochondrion outer membrane, rather than in the matrix to which it is targeted
Tissue Location Expressed in gonads, adrenal cortex and kidney.
Research Areas

BACKGROUND

Steroidogenic acute regulatory protein (StAR) plays a significant role in cholesterol transport from the cytoplasmic outer membrane to the inner mitochondrial membrane.

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