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>   首页   >   产品   >   一抗   >   精选抗体   >   磷酸化抗体   >   Phospho-Acetyl Coenzyme A Carboxylase (Ser79) Rabbit mAb   

Phospho-Acetyl Coenzyme A Carboxylase (Ser79) Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q13085
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 265554 Da
Additional Information
Gene ID 31
Other Names ACACA
Dilution WB~~1/500-1/1000
Format Liquid
Protein Information
Name ACACA (HGNC:84)
Synonyms ACAC, ACC1, ACCA
Function Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20457939, PubMed:20952656, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20457939, PubMed:20952656, PubMed:29899443).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5SWU9}
Tissue Location Expressed in brain, placenta, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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