癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Calbindin Rabbit mAb
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Application 
| WB, IHC-P, IP |
|---|---|
| Primary Accession | P12658 |
| Reactivity | Rat, Mouse |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Purification | Affinity Purified |
| Calculated MW | 29994 Da |
| Gene ID | 12307 |
|---|---|
| Other Names | Calb1 |
| Dilution | WB~~1:500-1:1000 IHC-P~~1:50~200 IP~~1:20-1:50 |
| Format | Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Calb1 |
|---|---|
| Function | Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. |
| Tissue Location | Expressed in the modiolar nerve root and in bushy neurons in the ventral cochlear nucleus (at protein level) |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Enables calcium ion binding activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium ion binding activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in metanephros development and retina layer formation. Acts upstream of or within locomotory behavior. Located in several cellular components, including axon; dendrite; and neuronal cell body. Is active in GABA-ergic synapse; glutamatergic synapse; and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human CALB1 (calbindin 1).
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