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ERCC1 Rabbit mAb

     
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Product Information
Primary Accession P07992
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 32562 Da
Additional Information
Gene ID 2067
Other Names ERCC1
Format Liquid
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name ERCC1
Function [Isoform 1]: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Cellular Location [Isoform 1]: Nucleus [Isoform 3]: Nucleus
Research Areas
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