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FBP1 Rabbit mAb

     
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Product Information
Primary Accession P09467
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 36842 Da
Additional Information
Gene ID 2203
Other Names FBP1
Format Liquid
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name FBP1
Synonyms FBP
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Tissue Location Expressed in pancreatic islets.
Research Areas
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