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>   首页   >   产品   >   一抗   >   其他   >   TFG Rabbit mAb   

TFG Rabbit mAb

     
  • 1 - TFG Rabbit mAb AP76206
    Western blot analysis of TRK fused gene in K562, rat Brain, C6, 3T3, Hela lysates using TFG antibody.
  • 2 - TFG Rabbit mAb AP76206
    Immunohistochemistry analysis of paraffin-embedded Human tonsil using TRK fused gene antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, IP
Primary Accession Q92734
Reactivity Rat, Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 43448 Da
Additional Information
Gene ID 10342
Other Names TFG
Dilution WB~~1:1000-1:5000
IHC-P~~1:50~200
IP~~1:10-1:100
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name TFG
Function Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858).
Cellular Location Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:21478858, PubMed:27813252).
Tissue Location Ubiquitous.
Research Areas

BACKGROUND

There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.

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