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>   首页   >   产品   >   一抗   >   其他   >   Hex Rabbit mAb   

Hex Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IP
Primary Accession Q03014
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 30022 Da
Additional Information
Gene ID 3087
Other Names HHEX
Dilution WB~~1/500-1/1000
IP~~N/A
Format Liquid
Protein Information
Name HHEX
Synonyms HEX, PRH, PRHX
Function Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT- signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). Inhibits EIF4E-mediated mRNA nuclear export (PubMed:12554669). May play a role in hematopoietic differentiation (PubMed:8096636).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P43120}. Nucleus, nuclear body. Cytoplasm
Tissue Location Liver and promyelocytic leukemia cell line HL-60.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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