p23 Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IP, ICC |
---|---|
Primary Accession | Q15185 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 18697 Da |
Gene ID | 10728 |
---|---|
Other Names | PTGES3 |
Dilution | WB~~1/500-1/1000 IP~~1/20 ICC~~N/A |
Format | Liquid |
Name | PTGES3 |
---|---|
Synonyms | P23, TEBP |
Function | Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q3ZBF7}. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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