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>   首页   >   产品   >   一抗   >   其他   >   S100 alpha 6 Rabbit mAb   

S100 alpha 6 Rabbit mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P06703
Reactivity Rat, Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 10180 Da
Additional Information
Gene ID 6277
Other Names S100A6
Dilution WB~~1:1000
FC~~1:10~50
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name S100A6
Synonyms CACY
Function May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Cellular Location Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side
Research Areas

BACKGROUND

S100A6 (calcyclin) is involved in a number of cellular processes, including exocytosis and cell cycle regulation. In addition, S100A6 interacts with a number of proteins such as SIP, GAPDH, and annexins in a calcium-dependent fashion. Research studies demonstrate that a down regulation of corresponding S100A6 gene expression causes a decrease in cell proliferation.

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