CBS Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, IHC-P, IF, ICC |
---|---|
Primary Accession | P35520 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Isotype | IgG |
Conjugate | Unconjugated |
Immunogen | A synthesized peptide derived from human CBS |
Purification | Affinity Chromatography |
Calculated MW | 60587 Da |
Gene ID | 102724560;875 |
---|---|
Other Names | CBS |
Dilution | WB~~1/500-1/1000 IHC-P~~N/A IF~~1:50~200 ICC~~N/A |
Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Name | CBS |
---|---|
Function | Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:20506325, PubMed:23974653, PubMed:23981774). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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