CCL19 beta Rabbit mAb
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | Q99731 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Immunogen | A synthesized peptide derived from human CCL19 |
| Purification | Affinity Chromatography |
| Calculated MW | 10993 Da |
| Gene ID | 6363 |
|---|---|
| Other Names | CCL19 |
| Dilution | WB~~1/500-1/1000 |
| Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CCL19 |
|---|---|
| Synonyms | ELC, MIP3B, SCYA19 |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta- arrestin (ARRB1/2) to ACKR4. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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