CTGF Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
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- 实验流程
- 背景知识
Application ![]()
| IHC-P, WB, E |
---|---|
Primary Accession | P29279 |
Other Accession | Q9R1E9, O19113, P29268, O18739, NP_001892 |
Reactivity | Human, Rat, Mouse |
Predicted | Bovine, Mouse, Pig, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38091 Da |
Antigen Region | 315-349 aa |
Gene ID | 1490 |
---|---|
Other Names | Connective tissue growth factor, CCN family member 2, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8, CTGF, CCN2, HCS24, IGFBP8 |
Target/Specificity | This CTGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-349 amino acids from the C-terminal region of human CTGF. |
Dilution | IHC-P~~1:100~500 WB~~1:1000 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CTGF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCN2 (HGNC:2500) |
---|---|
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor- induced DNA synthesis. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P29268}. Secreted |
Tissue Location | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
For Research Use Only. Not For Use In Diagnostic Procedures.

Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Connective tissue growth factor (CTGF), a member of the CCN family of secreted matricellular proteins, regulates fibrosis, angiogenesis, cell proliferation, apoptosis, tumor growth, and metastasis.
REFERENCES
Li,M.H., Mol. Cancer Res. 6 (10), 1649-1656 (2008)
Bogatkevich,G.S., Am. J. Physiol. Lung Cell Mol. Physiol. 295 (4), L603-L611 (2008)
Zhang,P., Tohoku J. Exp. Med. 215 (3), 199-206 (2008)

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