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KLF10 Rabbit mAb

     
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Product Information
Primary Accession Q13118
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 52555 Da
Additional Information
Gene ID 7071
Other Names KLF10
Format Liquid
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name KLF10
Synonyms TIEG, TIEG1
Function Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation.
Cellular Location Nucleus {ECO:0000250|UniProtKB:O89091}.
Research Areas
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