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SARS2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SARS2 Antibody (Center) AP7837c
    Western blot analysis of SARS2 Antibody (Center) (Cat. #AP7837c) in Hela cell line lysates (35ug/lane). SARS2 (arrow) was detected using the purified Pab.
  • 14 - SARS2 Antibody (Center) AP7837c
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with SARS2 antibody (Center) (Cat.#AP7837c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q9NP81
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 58283 Da
Antigen Region 315-344 aa
Additional Information
Gene ID 54938
Other Names Serine--tRNA ligase, mitochondrial, SerRSmt, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase, SARS2, SARSM
Target/Specificity This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-344 amino acids from the Central region of human SARS2.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSARS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SARS2
Synonyms SARSM
Function Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Cellular Location Mitochondrion matrix {ECO:0000250|UniProtKB:Q9N0F3}
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

SARS2 catalyzes the attachment of serine to tRNA(Ser). It is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).

REFERENCES

Muller,T., Acta Neuropathol. 110 (4), 426-430 (2005)
Gibbons,W.J. Jr., Biochem. Biophys. Res. Commun. 317 (3), 774-778 (2004)
Yokogawa,T., J. Biol. Chem. 275 (26), 19913-19920 (2000)

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