Phospho-GATA3 (Ser308) Rabbit mAb
- 产品详情
- 实验流程
| Primary Accession | P23771 |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 47916 Da |
| Gene ID | 2625 |
|---|---|
| Other Names | GATA3 |
| Format | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GATA3 |
|---|---|
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages. |
| Cellular Location | Nucleus. |
| Tissue Location | T-cells and endothelial cells. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Discontinued
Cat# AP78548
Size:
50 µl
100 µl
Price:
¥ 1,250.00
¥ 2,050.00
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