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QDPR Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - QDPR Antibody (C-term) AP8841b
    Anti-QDPR Antibody (C-term) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - QDPR Antibody (C-term) AP8841b
    Western blot analysis of QDPR Antibody (C-term) (Cat. #AP8841b) in mouse liver tissue lysates (35ug/lane). QDPR (arrow) was detected using the purified Pab.
  • 14 - QDPR Antibody (C-term) AP8841b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with QDPR Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • 1 - QDPR Antibody (C-term) AP8841b
    Western blot analysis of QDPR (arrow) using rabbit polyclonal QDPR Antibody (C-term) (Cat. #AP8841b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the QDPR gene.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P09417
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 25790 Da
Antigen Region 218-243 aa
Additional Information
Gene ID 5860
Other Names Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase, QDPR, DHPR
Target/Specificity This QDPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-243 amino acids from the C-terminal region of human QDPR.
Dilution WB~~1:1000
IHC-P~~1:100~500
E~~Use at an assay dependent concentration.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsQDPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name QDPR
Synonyms DHPR, SDR33C1
Function Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

BACKGROUND

QDPR is the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems.

REFERENCES

Schnetz-Boutaud,N.C., et.al.,Genes Brain Behav. 8 (8), 753-757 (2009)

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