p21 Antibody

Rabbit mAb

Western blot analysis of p21 in (1) MCF-7 cell lysate; (2) LnCaP cell lysate.
Immunohistochemical analysis of paraffin-embedded human colon, using p21 Antibody.
Immunofluorescent analysis of MCF7 cells, using p21 Antibody .
Expression of estrogen receptors and androgen receptor and their clinical significance in gastric cancer. -Oncotarget

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC, IF, ICC, IP, IHF
Primary Accession	P38936
Reactivity	Human
Clonality	Monoclonal
Other Names	CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; P21cip1;
Isotype	Rabbit IgG
Host	Rabbit
Calculated MW	21 KDa

Additional Information
Dilution	WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
Purification	Affinity-chromatography
Immunogen	A synthesized peptide derived from human p21
Description	The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.
Storage Condition and Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.