Paxillin Antibody

Rabbit mAb

Western blot analysis of Paxillin expression in HeLa cell lysate.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Paxillin Antibody.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC, IF, ICC, IP, IHF
Primary Accession	P49023
Reactivity	Rat, Human, Mouse
Clonality	Monoclonal
Other Names	Paired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha;
Isotype	Rabbit IgG
Host	Rabbit
Calculated MW	60 KDa

Additional Information
Dilution	WB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:50
Purification	Affinity-chromatography
Immunogen	A synthesized peptide derived from human Paxillin
Description	Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.
Storage Condition and Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.