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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   CCR3 Antibody    

CCR3 Antibody

Rabbit mAb

     
  • 1 - CCR3 Antibody   AP90562
    Western blot analysis of CCR3 expression in K562 cell lysate.
  • 2 - CCR3 Antibody   AP90562
    Immunohistochemical analysis of paraffin-embedded human epidemal cells of skin, using CCR3 Antibody .
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, ICC, IHF
Primary Accession P51677
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Other Names CCR3; CD193; CCCKR3; CMKBR3; CKR3; CMKBR1L2; C-C chemokine receptor type 3;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 41044 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human CCR3
Description Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name CCR3
Synonyms CMKBR3
Function Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location In eosinophils as well as trace amounts in neutrophils and monocytes.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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