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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   Cytokeratin 10 Antibody   

Cytokeratin 10 Antibody

Rabbit mAb

     
  • 0 - Cytokeratin 10 Antibody AP90586
    Western blot analysis of Cytokeratin 10 expression in A431 cell lysate.
  • 0 - Cytokeratin 10 Antibody AP90586
    Immunohistochemical analysis of paraffin-embedded human bladder, using Cytokeratin 10 Antibody.
  • 0 - Cytokeratin 10 Antibody AP90586
    Immunofluorescent analysis of HACAT cells, using Cytokeratin 10 Antibody.
  • 产品详情
  • 实验流程
Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, ICC, IHF
Primary Accession P13645
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Other Names CK-10; CK10; cytokeratin 10; Cytokeratin-10; K10; K1C10; keratin 10; Keratin, type I cytoskeletal 10; Keratin-10; KPP; KRT10;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 58827 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Cytokeratin 10
Description K10 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name KRT10
Synonyms KPP
Function Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).
Cellular Location Secreted, extracellular space. Cell surface. Cytoplasm
Tissue Location Seen in all suprabasal cell layers including stratum corneum. Expressed on the surface of lung cell lines (PubMed:19627498). Localized on the surface of desquamated nasal epithelial cells (at protein level) (PubMed:12427098)
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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