PEBP1 Antibody

Rabbit mAb

Western blot analysis of PEBP1 expression in A549 cell lysate.
Immunohistochemical analysis of paraffin-embedded human liver, using PEBP1 Antibody.
Immunofluorescent analysis of Hela cells, using PEBP1 Antibody.

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC, IF, ICC, IP, IHF
Primary Accession	P30086
Reactivity	Rat, Human, Mouse
Clonality	Monoclonal
Other Names	PEBP1; HCNP; PBP; PEBP; RKIP;
Isotype	Rabbit IgG
Host	Rabbit
Calculated MW	21 KDa

Additional Information
Dilution	WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20
Purification	Affinity-chromatography
Immunogen	A synthesized peptide derived from human PEBP1
Description	Raf kinase inhibitor protein (RKIP) is a member of the phosphatidylethanolamine-binding protein (PEBP) family that associates with Raf-1 and the MEK and MAP kinases. RKIP has been shown to complex with Raf-1, MEK, and ERK. Although MEK and ERK can simultaneously bind RKIP, the association between Raf-1 and RKIP and that of RKIP and MEK are mutually exclusive. Thus, RKIP competitively disrupts the Raf-1-MEK complex and effectively terminates signal transmission from Raf-1 to MAP kinases.
Storage Condition and Buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.