TBR1 Antibody
Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB |
---|---|
Primary Accession | Q16650 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Other Names | T box brain 1; T-brain-1; TBR 1; Tbr1; TES 56; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 74053 Da |
Dilution | WB 1:500~1:2000 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human TBR1 |
Description | Probable transcriptional regulator involved in developmental processes. Required for normal brain development. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | TBR1 |
---|---|
Function | Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection (PubMed:25232744, PubMed:30250039). As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons (By similarity). |
Cellular Location | Nucleus |
Tissue Location | Brain. |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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