KIR3DL3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- 产品详情
- 实验流程
- 背景知识
Application ![]()
| WB, IHC-P, FC, E |
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Primary Accession | Q8N743 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 44928 Da |
Antigen Region | 132-158 aa |
Other Names | Killer cell immunoglobulin-like receptor 3DL3, CD158 antigen-like family member Z, Killer cell inhibitory receptor 1, CD158z, KIR3DL3, CD158Z, KIR3DL7, KIRC1 |
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Target/Specificity | This KIR3DL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-158 amino acids from the Central region of human KIR3DL3. |
Dilution | WB~~1:1000 IHC-P~~1:100~500 FC~~1:10~50 E~~Use at an assay dependent concentration. |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KIR3DL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KIR3DL3 |
---|---|
Synonyms | CD158Z, KIR3DL7, KIRC1 |
Function | Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
For Research Use Only. Not For Use In Diagnostic Procedures.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
KIR3DL3 is transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. This protein are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).
REFERENCES
Trompeter,H.I., et.al., J. Immunol. 174 (7), 4135-4143 (2005)
Arnheim,L., et.al., Tissue Antigens 65 (3), 252-259 (2005)

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