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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   NPRC Antibody   

NPRC Antibody

Rabbit mAb

     
  • 1 - NPRC Antibody AP91735
    Western blot analysis of Natriuretic Peptide Receptor C expression in HeLa cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P17342
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Other Names ANPC; ANPRC; GUCY2B; NPR 3; NPR C; Npr3; NPRC;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 59808 Da
Additional Information
Dilution WB 1:500~1:2000 FC 1:100
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Natriuretic Peptide Receptor C
Description Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name NPR3
Synonyms ANPRC, C5orf23, NPRC
Function Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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