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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   NPRC Antibody   

NPRC Antibody

Rabbit mAb

     
  • 1 - NPRC Antibody AP91735
    Western blot analysis of Natriuretic Peptide Receptor C expression in HeLa cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC
Primary Accession P17342
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Other Names ANPC; ANPRC; GUCY2B; NPR 3; NPR C; Npr3; NPRC;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 59808 Da
Additional Information
Dilution WB 1:500~1:2000 FC 1:100
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Natriuretic Peptide Receptor C
Description Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name NPR3
Synonyms ANPRC, C5orf23, NPRC
Function Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
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