NPRC Antibody
Rabbit mAb
- 产品详情
- 实验流程
Application ![]()
| WB, FC |
---|---|
Primary Accession | P17342 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Other Names | ANPC; ANPRC; GUCY2B; NPR 3; NPR C; Npr3; NPRC; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 59808 Da |
Dilution | WB 1:500~1:2000 FC 1:100 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Natriuretic Peptide Receptor C |
Description | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | NPR3 |
---|---|
Synonyms | ANPRC, C5orf23, NPRC |
Function | Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. Acts as a regulator of osteoblast differentiation and bone growth by binding to its ligand osteocrin, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Research Areas
For Research Use Only. Not For Use In Diagnostic Procedures.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.

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