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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   Retinoic Acid Receptor beta Antibody   

Retinoic Acid Receptor beta Antibody

Rabbit mAb

     
  • 1 - Retinoic Acid Receptor beta Antibody AP91833
    Western blot analysis of Retinoic Acid Receptor beta expression in MCF7 cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC, IF, ICC, IHF
Primary Accession P10826
Reactivity Human
Clonality Monoclonal
Other Names HAP; NR1B2; RAR B; RAR beta; RAR epsilon; RARB; RRB2;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 50489 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human Retinoic Acid Receptor beta
Description Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name RARB
Synonyms HAP, NR1B2
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (PubMed:12554770). The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element (PubMed:29021580). In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
Cellular Location Nucleus. Cytoplasm [Isoform Beta-2]: Nucleus.
Tissue Location Expressed in aortic endothelial cells (at protein level).
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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