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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   HB EGF Antibody   

HB EGF Antibody

Rabbit mAb

     
  • 1 - HB EGF Antibody AP92112
    Western blot analysis of HB EGF expression in K562 cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99075
Reactivity Rat, Human
Clonality Monoclonal
Other Names DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 23067 Da
Additional Information
Dilution WB 1:500~1:2000
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human HB EGF
Description May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name HBEGF
Synonyms DTR, DTS, HEGFL
Function Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Cellular Location [Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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