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>   首页   >   产品   >   重组兔单克隆抗体   >   重组兔单克隆抗体   >   HIRA Antibody   

HIRA Antibody

Rabbit mAb

     
  • 1 - HIRA Antibody AP92496
    Western blot analysis of HIRA expression in HeLa cell lysate.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, FC, ICC, IP
Primary Accession P54198
Reactivity Human
Clonality Monoclonal
Other Names DGCR1; HIR; HIRA; TUP 1; TUPLE1;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 111835 Da
Additional Information
Dilution WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:100
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human HIRA
Description Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name HIRA
Synonyms DGCR1, HIR, TUPLE1
Function Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Cellular Location Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus. Localizes to PML bodies immediately prior to onset of senescence
Tissue Location Expressed at high levels in kidney, pancreas and skeletal muscle and at lower levels in brain, heart, liver, lung, and placenta.
Research Areas

For Research Use Only. Not For Use In Diagnostic Procedures.

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