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POK6 Rabbit Polyclonal Antibody

POK6 Rabbit Polyclonal Antibody

     
  • 1 - POK6 Rabbit Polyclonal Antibody AP93412
    Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession P63133
Reactivity Human, Rat, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 107703 Da
Additional Information
Other Names Endogenous retrovirus group K member 8 Pol protein, HERV-K115 Pol protein, HERV-K_8p23.1 provirus ancestral Pol protein, Reverse transcriptase, RT, 2.7.7.49, Ribonuclease H, RNase H, 3.1.26.4, Integrase, IN, ERVK-8
Dilution WB~~1:1000
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name ERVK-8
Function Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA. The RNase H domain of the reverse transcriptase performs two functions. It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid. Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome. Endogenous Pol proteins may have kept, lost or modified their original function during evolution.
Research Areas
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