癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
STB5L Rabbit Polyclonal Antibody
STB5L Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q9Y2K9 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 131887 Da |
| Gene ID | 9515 |
|---|---|
| Other Names | Syntaxin-binding protein 5-like, Lethal(2) giant larvae protein homolog 4, Tomosyn-2, STXBP5L, KIAA1006, LLGL4 |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | STXBP5L |
|---|---|
| Synonyms | KIAA1006, LLGL4 |
| Function | Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth (PubMed:25504045). |
| Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein. Membrane; Peripheral membrane protein Note=Cytoplasmic, and associated with vesicular membranes and the plasma membrane. |
| Tissue Location | Detected in kidney, hippocampus and lung carcinoma. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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