癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
S35G1 Rabbit Polyclonal Antibody
S35G1 Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application 
| WB |
|---|---|
| Primary Accession | Q2M3R5 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 39836 Da |
| Gene ID | 159371 |
|---|---|
| Other Names | Solute carrier family 35 member G1, Partner of STIM1, Transmembrane protein 20, SLC35G1, C10orf60, POST, TMEM20 |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLC35G1 {ECO:0000303|PubMed:39508819, ECO:0000312|HGNC:HGNC:26607} |
|---|---|
| Function | Chloride-sensitive citrate transporter localized on the basolateral membrane of enterocytes that mediates efflux of citrate into the bloodstream (PubMed:39508819). May also play a role in intracellular calcium sensing and homeostasis by acting as a negative regulator of plasma membrane calcium-transporting ATPases, thereby preventing calcium efflux from the cell (PubMed:22084111). |
| Cellular Location | Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane |
| Tissue Location | Highly expressed in the digestive tract, especially in the upper part of the small intestine, including the duodenum and jejunum, followed by the testis and pancreas |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016],
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