ATS3 Rabbit Polyclonal Antibody
ATS3 Rabbit Polyclonal Antibody
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Application
| WB |
|---|---|
| Primary Accession | O15072 |
| Reactivity | Human, Rat, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 135603 Da |
| Gene ID | 9508 |
|---|---|
| Other Names | A disintegrin and metalloproteinase with thrombospondin motifs 3, ADAM-TS 3, ADAM-TS3, ADAMTS-3, 3.4.24.-, Procollagen II N-proteinase, PC II-NP, Procollagen II amino propeptide-processing enzyme, ADAMTS3, KIAA0366 |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ADAMTS3 |
|---|---|
| Synonyms | KIAA0366 |
| Function | Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens. |
| Cellular Location | Secreted. Secreted, extracellular space, extracellular matrix |
| Tissue Location | Found in cartilage and skin. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. [provided by RefSeq, Feb 2016],
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