PRPC Rabbit Polyclonal Antibody
PRPC Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
- 背景知识
Application
| WB |
|---|---|
| Primary Accession | P02810 |
| Reactivity | Human, Rat, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 17015 Da |
| Gene ID | 5554;5555 |
|---|---|
| Other Names | Salivary acidic proline-rich phosphoprotein 1/2, Db-s, PRP-1/PRP-2, Parotid acidic protein, Pa, Parotid double-band protein, Parotid isoelectric focusing variant protein, PIF-S, Parotid proline-rich protein 1/2, Pr1/Pr2, Protein C, Salivary acidic proline-rich phosphoprotein 1/2, Salivary acidic proline-rich phosphoprotein 3/4, Db-F, PIF-F, PRP-3/PRP-4, Protein A, Peptide P-C, PRH1 |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | PRH1 |
|---|---|
| Function | PRP's act as highly potent inhibitors of crystal growth of calcium phosphates. They provide a protective and reparative environment for dental enamel which is important for the integrity of the teeth. |
| Cellular Location | Secreted. |
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid and submandibular/sublingual glands. Multiple distinct alleles of this locus including the parotid isoelectric-focusing variant slow (PIF-s), the parotid acidic protein (Pa), and the double band slow (Db-s) isoforms have been characterized. The reference genome encodes the Db-s allele. Certain alleles of this gene are associated with susceptibility to dental caries. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Co-transcription of this gene with adjacent genes has been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015],
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