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TTC18 Rabbit Polyclonal Antibody

TTC18 Rabbit Polyclonal Antibody

     
  • 1 - TTC18 Rabbit Polyclonal Antibody AP93513
    Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q5T0N1
Reactivity Human, Rat, Mouse
Host Polyclonal, Rabbit,IgG
Clonality Polyclonal
Calculated MW 125721 Da
Additional Information
Gene ID 118491
Other Names Cilia- and flagella-associated protein 70 {ECO:0000312|HGNC:HGNC:30726}, Tetratricopeptide repeat protein 18, TPR repeat protein 18, CFAP70 (HGNC:30726)
Dilution WB~~1:1000
Storage Conditions-20℃

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name CFAP70 (HGNC:30726)
Function Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length. Essential for the assembly of the sperm flagellum and the correct shaping of the sperm head, during spermiogenesis.Contributes in part to flagellar biogenesis by stabilizing QRICH2, promoting the cytoplasmic preassembly of CFAP61 and CFAP91, and regulating the manchette localization of axoneme-associated proteins such as IFT88, DNAI1 and CFAP61.
Cellular Location Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium {ECO:0000250|UniProtKB:D3YVL2}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:D3YVL2}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:D3YVL2} Note=Present all along the flagellum, with a marked signal at the base of the flagellum (PubMed:31621862). Localizes to the central apparatus of the flagellar axoneme (By similarity) {ECO:0000250|UniProtKB:D3YVL2, ECO:0000269|PubMed:31621862}
Tissue Location Expressed in testis.
Research Areas
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