TTC18 Rabbit Polyclonal Antibody
TTC18 Rabbit Polyclonal Antibody
- 产品详情
- 实验流程
Application
| WB |
|---|---|
| Primary Accession | Q5T0N1 |
| Reactivity | Human, Rat, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 125721 Da |
| Gene ID | 118491 |
|---|---|
| Other Names | Cilia- and flagella-associated protein 70 {ECO:0000312|HGNC:HGNC:30726}, Tetratricopeptide repeat protein 18, TPR repeat protein 18, CFAP70 (HGNC:30726) |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | CFAP70 (HGNC:30726) |
|---|---|
| Function | Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length. Essential for the assembly of the sperm flagellum and the correct shaping of the sperm head, during spermiogenesis.Contributes in part to flagellar biogenesis by stabilizing QRICH2, promoting the cytoplasmic preassembly of CFAP61 and CFAP91, and regulating the manchette localization of axoneme-associated proteins such as IFT88, DNAI1 and CFAP61. |
| Cellular Location | Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium {ECO:0000250|UniProtKB:D3YVL2}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:D3YVL2}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:D3YVL2} Note=Present all along the flagellum, with a marked signal at the base of the flagellum (PubMed:31621862). Localizes to the central apparatus of the flagellar axoneme (By similarity) {ECO:0000250|UniProtKB:D3YVL2, ECO:0000269|PubMed:31621862} |
| Tissue Location | Expressed in testis. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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