Recombinant Anti-Glycerol Kinase 1 Rabbit mAb
- 产品详情
- 实验流程
Application
| WB, FC, IP |
|---|---|
| Primary Accession | P32189 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal |
| Calculated MW | 61245 Da |
| Gene ID | 2710 |
|---|---|
| Other Names | Glycerol kinase; GK; Glycerokinase; ATP:glycerol 3-phosphotransferase |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within human Glycerol Kinase 1 protein. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) FC~~1:10~50 IP~~N/A |
| Format | Liquid in PBS, pH 7.3, 50% glycerol, 0.05% BSA, and 0.05% Proclin300. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | GK (HGNC:4289) |
|---|---|
| Function | Kinase that plays a key role in glycerol metabolism, catalyzing its phosphorylation to produce sn-glycerol 3-phosphate. Sn- glycerol 3-phosphate is a crucial intermediate in various metabolic pathways, such as the synthesis of glycerolipids and triglycerides, glycogenesis, glycolysis and gluconeogenesis. |
| Cellular Location | Mitochondrion outer membrane; Single-pass membrane protein. Nucleus. Cytoplasm, cytosol. Note=Glycerol kinase activity is more cytosolic in some tissues. It probably represents the expression of isoforms lacking a transmembrane domain [Isoform 4]: Cytoplasm, cytosol. Note=In adult tissues, such as liver the glycerol kinase activity is more cytosolic. It probably represents the expression of this isoform which lacks a transmembrane domain |
| Tissue Location | [Isoform 2]: Widely expressed in fetal and adult tissues. [Isoform 4]: The sole isoform expressed in adult liver and kidney. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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