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GGT7 light chain Rabbit pAb

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Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, E
Predicted	Rat, Pig, Human, Mouse, Rabbit, Horse, Sheep
Host	Rabbit
Clonality	Polyclonal
Calculated MW	21 KDa
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human GGT7 light chain
Epitope Specificity	581-662/662
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SUBCELLULAR LOCATION	Membrane; Single pass type II membrane protein.
SIMILARITY	Belongs to the gamma-glutamyltransferase family.
SUBUNIT	Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Isoform 3 interacts with FAM57A.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].

Additional Information
Gene ID	2686
Other Names	D20S101; GGT4; GGTL3; GGTL5; gamma-glutamyltransferase 7; gamma-glutamyltransferase-like 3
Target/Specificity	Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.
Dilution	WB=1:500-2000,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Name	GGT7 light chain Rabbit pAb
Function	Cleaves glutathione conjugates.