癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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Upstream Binding Protein 1 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q86Y57 |
| Other Accession | Q86Y57 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 60 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Upstream Binding Protein 1 |
| Epitope Specificity | 351-450/540 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the grh/CP2 family. CP2 subfamily. |
| SUBUNIT | Interacts with TFCP2. Interacts with PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Gene ID | 7342 |
|---|---|
| Other Names | LBP-1B; LBP-1a; LBP1A; LBP1B; Cp2b; NF2d9; RGD1564700; Q86Y57_HUMAN; UBIP1_HUMAN; UBP1; Transcription factor LBP-1; LBP1; Q60786_MOUSE; UBIP1_MOUSE; Nuclear factor 2d9 (NF2d9); Q8BH21_MOUSE; upstream binding protein 1 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Upstream Binding Protein 1 Rabbit pAb |
|---|---|
| Function | UBP1 is an important SF1 independent transcriptional activator stimulating P450scc expression in human placental JEG 3 cells. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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