癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
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Kinesin C2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | Q96AC6 |
| Other Accession | Q96AC6 |
| Reactivity | Mouse |
| Predicted | Rat, Human, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 90147 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Kinesin C2 |
| Epitope Specificity | 181-280/838 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIFC2 is 792 amino acid member of the C-terminal motor family specifically expressed in both the central and peripheral nervous systems in nonproliferative cells. KIFC2 accumulates at the proximal and distal sides of axons and is a minus-end-directed kinesin. KIFC2 localizes with some, but not all, axonally transported organelles. KIFC2 may be involved in retrograde axonal transport. |
| Gene ID | 90990 |
|---|---|
| Other Names | KIFC2_HUMAN; KIFC2; KIFC2_MOUSE; kinesin family member C2 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | KIFC2 |
|---|---|
| Function | May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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¥ 1,250.00
Cat# AP96340
