癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
SLC12A8 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | A0AV02 |
| Other Accession | A0AV02 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 78239 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SLC12A8 |
| Epitope Specificity | 501-600/714 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SIMILARITY | Belongs to the SLC12A transporter family. |
| DISEASE | Note=SLC12A8 has been identified as a possible susceptibility gene for psoriasis mapped to chromosome 3q21 (PSORS5). |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene is thought to be a candidate for psoriasis susceptibility. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2010] Function : Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. Subcellular Location : Membrane. |
| Gene ID | 84561 |
|---|---|
| Other Names | CCC9; S12A8_HUMAN; SLC12A8; Cation-chloride cotransporter 9; solute carrier family 12 member 8; solute carrier family 12 (sodium/potassium/chloride transporters), member 8 |
| Dilution | WB=1:500-2000,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | SLC12A8 |
|---|---|
| Synonyms | CCC9 |
| Function | Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. |
| Cellular Location | Membrane; Multi-pass membrane protein |
| Tissue Location | Ubiquitous with very low level in normal skin. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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