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ADAMTS7(NT) Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q6P7J9 |
| Other Accession | Q6P7J9 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 158 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ADAMTS7 |
| Epitope Specificity | 241-340/1595 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Contains 1 disintegrin domain.Contains 1 peptidase M12B domain.Contains 1 PLAC domain.Contains 8 TSP type-1 domains. |
| SUBUNIT | Interacts with COMP. |
| Post-translational modifications | N-glycosylated. O-glycosylated proteoglycan. Contains chondroitin sulfate (By similarity). May be cleaved by a furin endopeptidase (By similarity). The precursor is sequentially processed. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Metalloprotease that may play a role in the degradation of COMP. Binds 1 zinc ion per subunit. pH dependence: Optimum pH is between 7.5 and 9.5. [Subcellular location] Secreted, extracellular space, extracellular matrix (By similarity). Note=Also found associated with the external cell surface[Tissue specificity] Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. Up-regulated in articular cartilage and synovium from arthritis patients. |
| Gene ID | 11173 |
|---|---|
| Other Names | ADAM-TS 7; ADAM-TS7; ADAMTS-7; Q6P7J9_HUMAN; ATS7_HUMAN; ADAMTS7; 3.4.24.-; ADAM metallopeptidase with thrombospondin type 1 motif 7; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7; COMPase; a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | ADAMTS7(NT) Rabbit pAb |
|---|---|
| Function | Metalloprotease that may play a role in the degradation of COMP. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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