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SNAP Recombinant Mouse mAb

     
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Host Mouse
Clonality Recombinant
Physical State Liquid
Isotype IgG2B/lambda
Purity affinity purified by Protein G
Buffer 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY Belongs to the SNAP family.
SUBUNIT Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity).
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins.
Additional Information
Other Names SNAPA; 1500039N14Rik; RA81; SNAP-alpha; SNARE; a-SNAP; hyh; alpha-SNAP; SNAA_BOVIN; NAPA; N-ethylmaleimide-sensitive factor attachment protein alpha; SNAA_HUMAN; SNAA_MOUSE; SNAA_RAT; Snap; NSF attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; alpha SNAP; alpha soluble NSF attachment protein
Dilution WB=1:500-1000,ICC/IF=1:100-500
StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Name SNAP Recombinant Mouse mAb
Function Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

For Research Use Only. Not For Use In Diagnostic Procedures.

Research Areas
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