ABCA5 Rabbit pAb

Product Information
Application Applications Legend: E=ELISA WB=Western Blotting IHC=Immunohistochemistry IHC-P=Immunohistochemistry (Paraffin) IP=Immunoprecipitation IF=Immunofluorescence IC=Immunochemistry ICC=Immunocytochemistry FC=Flow Cytometry DB=Dot Blot	WB, IHC-P, IHC-F, IF, E
Host	Rabbit
Clonality	Polyclonal
Calculated MW	186 KDa
Physical State	Liquid
Immunogen	KLH conjugated synthetic peptide derived from human ABCA5
Epitope Specificity	1401-1500/1642
Isotype	IgG
Purity	affinity purified by Protein A
Buffer	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
SIMILARITY	Belongs to the ABC transporter superfamily. ABCA family. Contains 2 ABC transporter domains.
Post-translational modifications	N-glycosylated (By similarity).
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Background Descriptions	ABCA5 is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA5 is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. ABCA5 is localized in the lysosome, late endosome and Golgi apparatus membrane and is thought to play a role in the processing of autolysosomes.

Additional Information
Gene ID	23461
Other Names	ABCA5_HUMAN; ABCA5; ATP-binding cassette sub-family A member 5; 7.6.2.-; KIAA1888; ABCA5_MOUSE; ABCA5_RAT; ABC13; DEL17q24; EST90625; HTC3; HTGH; B930033A02Rik; mKIAA1888; zgc:163009; ATP binding cassette subfamily A member 5; ATP-binding cassette, sub-family A (ABC1), member 5
Dilution	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Name	ABCA5 Rabbit pAb
Function	May play a role in the processing of autolysosomes (By similarity).