癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
STK16 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Primary Accession | O75716 |
| Other Accession | O75716 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 34656 Da |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human STK16 |
| Epitope Specificity | 101-200/305 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. |
| Post-translational modifications | Autophosphorylated on serine and threonine residues. It is uncertain whether palmitoylation is on Cys-6 and/or Cys-8. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 8576 |
|---|---|
| Other Names | KRCT; MPSK; PKL12; PSK; TSF1; hPSK; EDPK; TSF-1; F52; STK16_HUMAN; STK16; Myristoylated and palmitoylated serine/threonine-protein kinase (MPSK); Protein kinase PKL12; TGF-beta-stimulated factor 1 (TSF-1); Tyrosine-protein kinase STK16; 2.7.11.1; MPSK1; STK16_MOUSE; Embryo-derived protein kinase (Edpk); Protein kinase Krct; STK16_RAT; serine/threonine kinase 16 |
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | STK16 |
|---|---|
| Synonyms | MPSK1, PKL12, TSF1 |
| Function | Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. |
| Cellular Location | Cytoplasm, perinuclear region. Membrane; Lipid-anchor. Note=Associates with Golgi and Golgi-derived vesicles. |
| Tissue Location | Ubiquitously expressed at very low levels. |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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