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PGAM1 Recombinant Rabbit mAb
- 产品详情
- 实验流程
Application 
| WB, IHC-P, IHC-F, IF |
|---|---|
| Reactivity | Rat, Human, Mouse |
| Host | Rabbit |
| Clonality | Recombinant |
| Physical State | Liquid |
| Immunogen | A synthesized peptide derived from human PGAMA1 |
| Epitope Specificity | 1-54/254 |
| Isotype | IgG/Kappa |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. |
| SUBUNIT | Homodimer. |
| Post-translational modifications | Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | PGAM1 belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It is involved in the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. |
| Other Names | HEL-S-35; PGAM-B; PGAMA; 2310050F24Rik; Pgam-1; Pgmut; PGAM1_HUMAN; PGAM1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B (PGAM-B); 5.4.2.11; 5.4.2.4; PGAM1_MOUSE; PGAM1_RAT; phosphoglycerate mutase 1; phosphoglycerate mutase 1 (brain); Phosphoglycerate mutase A, nonmuscle form |
|---|---|
| Dilution | WB=1:1000-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | PGAM1 Recombinant Rabbit mAb |
| Function | Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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