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Ghrelin Receptor Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ISR8 |
| Other Accession | Q6ISR8 |
| Predicted | Rat, Pig, Human, Mouse, Rabbit, Horse, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 41 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Ghrelin Receptor |
| Epitope Specificity | 75-135/366 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the G-protein coupled receptor 1 family. |
| DISEASE | Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a member of the G-protein coupledreceptor family. The encoded protein may play a role in energyhomeostasis and regulation of body weight. Two identifiedtranscript variants are expressed in several tissues and areevolutionary conserved in fish and swine. One transcript, 1a,excises an intron and encodes the functional protein; this proteinis the receptor for the Ghrelin ligand and defines a neuroendocrinepathway for growth hormone release. The second transcript (1b)retains the intron and does not function as a receptor for Ghrelin;however, it may function to attenuate activity of isoform 1a.Mutations in this gene are associated with autosomal idiopathicshort stature.[provided by RefSeq, Apr 2010]. |
| Gene ID | 2693 |
|---|---|
| Other Names | GHDP; GHS-R1a; GHSR-1a; C530020I22Rik; GHRP; GHS-R; Ghsr1a; Q6ISR8_HUMAN; GHSR_HUMAN; GHSR; GH-releasing peptide receptor (GHRP); Ghrelin receptor; GHSR_MOUSE; GHSR_PIG; GHSR_RAT; growth hormone secretagogue receptor |
| Dilution | WB=1:500-2000,ICC/IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
For Research Use Only. Not For Use In Diagnostic Procedures.
| Name | Ghrelin Receptor Rabbit pAb |
|---|---|
| Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). |
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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