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DPY19L2 Rabbit pAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Reactivity | Mouse |
| Predicted | Rat, Pig, Human, Rabbit, Dog, Horse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 87 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from mouse DPY19L2 |
| Epitope Specificity | 671-770/773 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SIMILARITY | Belongs to the dpy-19 family. |
| SUBUNIT | Membrane; Multi-pass membrane protein (Potential). |
| DISEASE | Defects in DPY19L2 are the cause of spermatogenic failure type 9 (SPGF9) [MIM:613958]. An infertility disorder caused by spermatogenesis defects. The most prominent feature is the malformation of the acrosome, which can be totally absent in most severe cases. Additional features are an abnormal nuclear shape and abnormal arrangement of the mitochondria of the spermatozoon. Note=Deletions in DPY19L2 are probably the major cause of SPGF9. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The protein encoded by this gene belongs to the dpy-19 family. It is highly expressed in testis, and is required for sperm head elongation and acrosome formation during spermatogenesis. Mutations in this gene are associated with an infertility disorder, spermatogenic failure type 9 (SPGF9). [provided by RefSeq, Dec 2011] |
| Other Names | SPATA34; SPGF9; 4932443J21Rik; Gm18376; D19L2_HUMAN; DPY19L2; Dpy-19-like protein 2; Protein dpy-19 homolog 2; 2.4.1.-; D19L2_MOUSE; dpy-19 like 2; dpy-19 like 2 (C. elegans); spermatogenesis associated 34 |
|---|---|
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | DPY19L2 Rabbit pAb |
| Function | Required during spermatogenesis for sperm head elongation and acrosome formation. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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