癌症的基本特征包括细胞增殖、血管生成、迁移、凋亡逃避机制和细胞永生等。找到癌症发生过程中这些通路的关键标记物和对应的抗体用于检测至关重要。
为您推荐一个泛素化位点预测神器——泛素化分析工具，可以为您的蛋白的泛素化位点作出预测和评分。
细胞自噬受体图形绘图工具为你的蛋白的细胞受体结合位点作出预测和评分，识别结合到自噬通路中的蛋白是非常重要的，便于让我们理解自噬在正常生理、病理过程中的作用，如发育、细胞分化、神经退化性疾病、压力条件下、感染和癌症。
Osteocalcin Mouse mAb
- 产品详情
- 实验流程
Application 
| WB |
|---|---|
| Reactivity | Human |
| Predicted | Rabbit |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 11 KDa |
| Physical State | Lyophilized or Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human Osteocalcin |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M PBS(pH7.4) |
| SIMILARITY | Belongs to the osteocalcin/matrix Gla protein family.Contains 1 Gla (gamma-carboxy-glutamate) domain. |
| Post-translational modifications | Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite. |
| Other Names | BGP; OC; OCN; Bglap2; Bgpr; Bgpra; OSTCN_BOVIN; BGLAP; Bone Gla protein (BGP); Gamma-carboxyglutamic acid-containing protein; OSTCN_HUMAN; OSTCN_PIG; OSTCN_RAT; bone gamma-carboxyglutamate protein; bone gamma-carboxyglutamate (gla) protein; osteocalcin; bone gla protein |
|---|---|
| Dilution | WB=1:500-2000 |
| Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| Name | Osteocalcin Mouse mAb |
| Function | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. |
For Research Use Only. Not For Use In Diagnostic Procedures.
Research Areas
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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